Networks

Gene network evolution.

When we undertook genome scans of tetraploid A. arenosa, we found that many of the genes showing evidence of selection are known to interact as proteins and/or function together in pathways or networks. How such interacting networks of proteins co-evolve or affect one anothers' evolutionary trajectories in natural populations and how this might affect their adaptive potential remains an intriguing question in evolutionary biology. Does co-evolution constrain them, or does it open new potential? In what ways to signals of selection perpetuate across gene networks? We are interested in using our sampling of >300 resequenced A. arenosa genomes from throughout the range to study the evolution of gene networks.